Protein name:
Carbonyl reductase [NADPH] 1 ;
Alternative:
20-beta-hydroxysteroid dehydrogenase ;1.1.1.197;15-hydroxyprostaglandin dehydrogenase [NADP+] ) ;Prostaglandin 9-ketoreductase ;NADPH-dependent carbonyl reductase 1 ;1.1.1.189;Prostaglandin-E(2) 9-reductase ) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MSSDRPVALV | TGANKGIGFA | IVRDLCRKFL | GDVVLTARDE | SRGHEAVKQL |
100:
QTEGLSPRFH | QLDIDNPQSI | RALRDFLLQE | YGGLNVLVNN | AGIAFKVVDP |
150:
TPFHIQAEVT | MKTNFFGTQD | VCKELLPIIK | PQGRVVNVSS | SVSLRALKSC |
200:
SPELQQKFRS | ETITEEELVG | LMNKFIEDAK | KGVHAKEGWP | NSAYGVTKIG |
250:
VTVLSRIYAR | KLNEERREDK | ILLNACCPGW | VRTDMAGPKA | TKSPEEGAET |
277:
PVYLALLPPG | AEGPHGQFVQ | DKKVEPW
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Pig
Rat
Bovine
Mouse
Rabbit
Human
ELISA Kit for Rat Carbonyl reductase [NADPH] 1
ELISA Kit for Rat Carbonyl reductase [NADPH] 1
ELISA Kit for Rat Carbonyl reductase [NADPH] 1
ELISA Kit for Rat Carbonyl reductase [NADPH] 1
ELISA Kit for Rat Carbonyl reductase [NADPH] 1
ELISA Kit for Rat Carbonyl reductase [NADPH] 1
CLIA Kit for Rat Carbonyl reductase [NADPH] 1
CLIA Kit for Rat Carbonyl reductase [NADPH] 1
CLIA Kit for Rat Carbonyl reductase [NADPH] 1
CLIA Kit for Rat Carbonyl reductase [NADPH] 1
CLIA Kit for Rat Carbonyl reductase [NADPH] 1
CLIA Kit for Rat Carbonyl reductase [NADPH] 1
Polyclonal Antibody for Rat Carbonyl reductase [NADPH] 1
Polyclonal Antibody for Rat Carbonyl reductase [NADPH] 1
Polyclonal Antibody for Rat Carbonyl reductase [NADPH] 1
Polyclonal Antibody for Rat Carbonyl reductase [NADPH] 1
Polyclonal Antibody for Rat Carbonyl reductase [NADPH] 1
Polyclonal Antibody for Rat Carbonyl reductase [NADPH] 1
Monoclonal Antibody for Rat Carbonyl reductase [NADPH] 1
Monoclonal Antibody for Rat Carbonyl reductase [NADPH] 1
Monoclonal Antibody for Rat Carbonyl reductase [NADPH] 1
Monoclonal Antibody for Rat Carbonyl reductase [NADPH] 1
Monoclonal Antibody for Rat Carbonyl reductase [NADPH] 1
Monoclonal Antibody for Rat Carbonyl reductase [NADPH] 1
Protein for Rat Carbonyl reductase [NADPH] 1
Protein for Rat Carbonyl reductase [NADPH] 1
Protein for Rat Carbonyl reductase [NADPH] 1
Protein for Rat Carbonyl reductase [NADPH] 1
Protein for Rat Carbonyl reductase [NADPH] 1
Protein for Rat Carbonyl reductase [NADPH] 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
strain :
Sprague-Dawley .
tissue :
Testis .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Spleen .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 6-14; 17-24 AND 59-71;IDENTIFICATION BY MASS SPECTROMETRY
strain :
Sprague-Dawley .
tissue :
Hippocampus .
tissue :
Spinal cord .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 104-138